Download PDF
Horm Metab Res 1973; 5(4): 279-282
DOI: 10.1055/s-0028-1093947
Originals

© Georg Thieme Verlag KG Stuttgart · New York

The Role of Transcortin in the Distribution of Corticosterone in the Rat

Zsuzsanna  Ács , E.  Stark
  • Institute of Experimental Medicine, Hungarian Academy of Sciences, Budapest, Hungary
Further Information

Publication History

Publication Date:
07 January 2009 (online)

Also available at
  PDF Download  Permissions and Reprints

Abstract

In rats treated with ACTH for 14 days, 24 hours after the last injection the plasma transcortin level is low. The biological half-life of corticosterone is of the same duration as in the controls; transcortin leaves it unaffected. The distribution volume of corticosterone is significantly higher in the treated than in the control animals and transcortin decreases it in both groups.

Key words

Plasma Transcortin - Corticosterone Biological Half-Life and Distribution Volume - ACTH Treatment

      >