Horm Metab Res 1972; 4(5): 337-341
DOI: 10.1055/s-0028-1094028
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Effect of Fasting and High-Fat Diet Feeding on Plasma and Pancreatic Insulin Contents in Young Chick Given an Oral Glucose Load[*]

K. L. Raheja , H. M. Tepperman , J.  Tepperman
  • Department of Pharmacology, State University of New York, Upstate Medical Center, Syracuse, New York, USA
Further Information

Publication History

Publication Date:
07 January 2009 (online)

Abstract

Experiments were conducted to determine the effect of fasting or high-fat diet feeding on the pancreatic insulin content and on the plasma insulin response of the chicks to an oral glucose load. Thirty-hour-old chicks not fed and one-week-old high-fat diet fed chicks showed a significant response. One-week-old mash-fed 30 hr fasted chicks showed a greater rise in insulin level in response to glycemic stimulus. On the other hand one-week-old mash-fed chicks showed the poorest response.

The pancreatic insulin content (units/100 gm body weight) of the 30 hr old chicks was significantly lower than those of other three groups.

The results suggest that chick when fasted or fed a highfat diet, in contrast to rat, maintains its responsiveness to a glycemic stimulus.

1 This work was supported in part by NIH grants AM 05410-10 and 5T 01 GM 00293

1 This work was supported in part by NIH grants AM 05410-10 and 5T 01 GM 00293

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