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Horm Metab Res 1972; 4(5): 377-379
DOI: 10.1055/s-0028-1094037
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© Georg Thieme Verlag KG Stuttgart · New York

Intravenous Glucose Tolerance and Insulin Secretion in the Rat after Thyroidectomy[*]

N.  Katsilambros [**] , R.  Ziegler , H.  Schatz [**] , M.  Hinz , V.  Maier , E. F. Pfeiffer [***]
  • Department of Endocrinology and Metabolism, Center of Internal Medicine and Pediatrics, University of Ulm, Germany
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Publication History

Publication Date:
07 January 2009 (online)

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Abstract

Thyroidectomy performed in rats resulted in decreased glucose assimilation and in reduction of the basal as well as the reactive serum insulin levels.

After thyroxin treatment of the thyroidectomized rats, the glucose assimilation and the serum IMI levels were restored and approached that observed in the normal rats. In the thyroidectomized animals, pancreas insulin content was lowered.

Key words

Intravenous Glucose Tolerance - Serum Insulin - Thyroidectomy - Hypothyroidism - Thyroxin Treatment - Pancreatic Insulin Content

1 Part of this paper was presented to the 6th Congress of the "Deutsche Diabetes-Gesellschaft", Düsseldorf, 14-15 May,1971.

1 Part of this paper was presented to the 6th Congress of the "Deutsche Diabetes-Gesellschaft", Düsseldorf, 14-15 May,1971.

2 Alexander von Humboldt Fellow. Present address: Ethnikis Trapezis 11, Filothei, Athens (Greece)

3 Supported by Deutsche Forschungsgemeinschaft, Bad Godesberg.

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