Horm Metab Res 1972; 4(3): 136-139
DOI: 10.1055/s-0028-1094086
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Insulin Levels in Nigerian Adults, Children and Pregnant Women

B. K. Adadevoh , F. A. Lukanmbi
  • Endocrine-Metabolic Research Laboratory and Metabolic Research Unit, Department of Chemical Pathology, University of Ibadan and University College Hospital, Ibadan, Nigeria
Further Information

Publication History

Publication Date:
07 January 2009 (online)

Abstract

Immunoreactive insulin (IRI) has been measured in a group of Nigerians. In 39 adults, 23 children and 34 pregnant women, IRI in morning blood samples showed high mean fasting levels which may be related to the traditional highcarbohydrate diet. Fasting plasma insulin levels were all below 53 µu/ml and values in males and non-pregnant women were respectively higher than in females and pregnant subjects. The values in children were noticeably higher than those reported from elsewhere and no progressive rise in plasma insulin with age was observed. Following an oral glucose dose in 32 adults, delayed maximal insulin response was generally observed. In 25% the pattern of insulin response was indicative of prediabetes. However, it is suggested that this rather high prediabetic rate may not represent the true incidence of the condition but may be partly influenced by gastrointestinal factors which may be peculiar to subjects in the environment.