The uptake of radioactive sulphate into chondroitin sulphate catalyzed by the hepatic
enzyme system of normal and pancreatectomized diabetic male rats was examined. It
was found that the enzymatic uptake of Iabeled sulphate into chondroitin sulphate
was stimulated with low concentrations (less than 1.0 mg) of soluble enzyme prepared
from livers of diabetic rats, whereas high concentrations (greater than 2.0 mg) of
diabetic enzyme protein non-competitively inhibited radioactive sulphate uptake.
Chondroitin Sulphate - Pancreatectomy in Rats
