Int J Sports Med 2009; 30(7): 485-488
DOI: 10.1055/s-0028-1104574
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Caffeine and Taurine Enhance Endurance Performance

T. F. Imagawa 1 , I. Hirano 2 , K. Utsuki 1 , M. Horie 1 , A. Naka 1 , K. Matsumoto 3 , S. Imagawa 1
  • 1Doctoral Program of Sports Medicine, University of Tsukuba, Tsukuba, Japan
  • 2School of Medicine, University of Tohoku, Senndai, Japan
  • 3Department of Clinical and Experimental Hematology, Doctoral Program in Advanced Biomedical Applications, University of Tsukuba, Tsukuba, Japan
Further Information

Publication History

accepted after revision August 19, 2008

Publication Date:
19 May 2009 (online)


Caffeine enhances endurance performance; however, its effect on accumulated lactate remains unclear. Conversely, taurine, which also enhances endurance performance, decreases accumulated lactate. In this study, the effect of combination of caffeine and taurine on endurance performance was assessed. Mice ran on a treadmill, and the accumulated lactate was measured. In addition, muscle fibers from the gastrocnemius muscle of the mice were stained with ATPase and analyzed. The use of caffeine and taurine over a 2 week period enhanced endurance performance. Moreover, taurine significantly decreased the accumulated concentration of lactate over long running distances. However, the diameter of the cross-sections and ratios of Types I, IIA, and IIB muscle fibers were not affected.


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Dr. S. ImagawaMD, PhD 

Doctoral Program of Sports Medicine

University of Tsukuba


1-1-1 D507



305-8577 Tsukuba


Phone: +81/29/853 30 45

Fax: +81/29/853 30 45