Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000002.xml
Aktuelle Dermatologie 2009; 35(5): 190-205
DOI: 10.1055/s-0028-1119695
DOI: 10.1055/s-0028-1119695
Fort- und Weiterbildung
© Georg Thieme Verlag KG Stuttgart · New York
Atopische Dermatitis
Atopic DermatitisFurther Information
Publication History
Publication Date:
30 April 2009 (online)

Dr. med. Margarete Niebuhr
Literatur
- 1 Maintz L, Novak N. Getting more and more complex: the pathophysiology of atopic eczema. Eur J Dermatol. 2007; 17 267-283
- 2 Boguniewicz M, Leung D Y. Atopic dermatitis. J Allergy Clin Immunol. 2006; 117 475-480
- 3 Akdis C A, Akdis M, Bieber T. et al . Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergy, Asthma and Immunology/PRACTALL Consensus report. J Allergy Clin Immunol. 2006; 118 152-169
- 4 Ozkaya E. Adult-onset of atopic dermatitis. J Am Acad Dermatol. 2005; 52 579-582
- 5 Williams H C, Stachan D P. The natural history of childhood eczema: observations from the British 1958 birth cohort study. Br J Dermatol. 1998; 139 834-839
- 6 Wüthrich B. Clinical aspects, epidemiology, and prognosis of atopic dermatitis. Ann Allergy Asthma Immunol. 1999; 83 464-470
- 7 Park J H, Choi Y L, Namburg J H. et al . Characteristics of extrinsic vs. intrinsic atopic dermatitis in infancy: correlations with laboratory variables. Br J Dermatol. 2006; 155 778-783
- 8 Schulz L F. Atopic dermatitis: a genetic-epidemiologic study in a population based twin sample. J Am Acad Dermatol. 1993; 28 719-723
- 9 Hoffjan S, Epplen J T. The genetics of atopic dermatitis: recent findings and future options. J Mol Med. 2005; 83 682-692
- 10 Cookson W O, Uhbi B, Lawrence R. et al . Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci. Nat Genet. 2001; 27 372-373
- 11 Weidinger S, Illig T, Baurecht H. et al . Loss of function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations. J Allergy Clin Immunol. 2006; 118 214-219
- 12 Illi S, von Mutius E, Lau S. et al . The natural course of atopic dermatitis from birth to age 7 years and the association with asthma. J Allergy Clin Immunol. 2004; 113 925-931
- 13 Schäfer T. Prävention des atopischen Ekzems – Evidenzbasierte Leitlinie. Der Hautarzt. 2005; 56 232-240
- 14 Chan L S, Robinson N, Xu L. Expression of interleukin-4 in the epidermis of transgenic mice results in a pruritic inflammatory skin disease: an experimental animal model to study atopic dermatitis. J Invest Dermatol. 2001; 117 977-983
- 15 Candi E, Schmidt R, Melino G. The cornified envelope: a model of cell death in the skin. Nat Rev Mol Cell Biol. 2005; 6 328-340
- 16 Strid J, Strobel S. Skin barrier dysfunction and systemic sensitization to allergens through the skin. Curr Drug Targets Inflamm Allergy. 2005; 4 531-541
- 17 Raap U, Ikoma A, Kapp A. Neurophysiology of pruritus. Hautarzt. 2006; 57 379-384
- 18 Dillon S R, Sprecher C, Hammond A. et al . Interleukin-31, a cytokine produced by activated T cells, induces dermatitis in mice. Nat Immunol. 2004; 5 752-760
- 19 Matsui K, Nishikawa A, Suto H. et al . Comparative study of Staphylococcus aureus isolated from lesional and non-lesional skin of atopic dermatitis. Microbiol Immunol. 2000; 44 945-947
- 20 Breuer K, Wittmann M, Bosche B. et al . Severe atopic dermatitis is associated with sensitization to staphylococcal enterotoxin B (SEB). Allergy. 2000; 55 551-555
- 21 Skov L, Olsen J V, Giorno R. et al . Application of staphylococcal enterotoxin B on normal and atopic skin induces up-regulation of T-cells by a superantigen-mediated mechanism. J Allergy Clin Immunol. 2000; 105 820-826
- 22 Ong P Y, Ohtake T, Brandt C. et al . Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Eng J Med. 2002; 347 1151-1160
- 23 Breuer K, Häussler S, Kapp A. et al . Staphylococcus aureus: colonizing features and influence of an antibacterial treatment in adults with atopic dermatitis. Br J Dermatol. 2002; 147 55-61
- 24 Howell M D, Wollenberg A, Gallo R L. et al . Cathelicidin deficiency predisposes to eczema herpeticatum. J Allergy Clin Immunol. 2006; 117 836-841
- 25 Schmid-Grendelmeier P, Scheynius A, Crameri R. The role of sensitization to Malassezia sympodialis in atopic eczema. Chem Immunol Allergy. 2006; 91 98-109
- 26 Schmid-Grendelmeier P, Fluckiger S, Disch R. et al . IgE-mediated and T cell-mediated autoimmunity against manganese superoxid dismutase in atopic dermatitis. J Allergy Clin Immunol. 2005; 115 1068-1075
- 27 Valenta R, Seiberler S, Natter S. et al . Autoallergy – a pathogenetic factor in atopic dermatitis. J Allergy Clin Immunol. 2000; 105 432-437
- 28 Schmid-Ott G, Jaeger B, Adamek C. et al . Levels of circulating CD8+ T lymphycytes, natural killer cells and eosinophils increase upon acute psychosocial stress in patients with atopic dermatitis. J Allergy Clin Immunol. 2001; 107 171-177
- 29 Toyoda M, Nakamura M, Makino T. et al . Nerve growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis. Br J Dermatol. 2002; 147 71-79
- 30 Turjanmaa K, Darsow U, Niggemann B. et al . EAACI/GA2LEN position paper: present status of the atopy patch test. Allergy. 2006; 61 1377-1384
- 31 Breuer K, Heratizadeh A, Wulf A. et al . Late eczematous reactions to food in children with atopic dermatitis. Clin Exp Allergy. 2004; 34 817-824
- 32 Breuer K, Wulf A, Constien A. et al . Birch pollen-related food as a provocation factor of allergic symptoms in children with atopic eczema/dermatitis syndrome. Allergy. 2004; 59 988-994
- 33 Reekers R, Busche M, Kapp A. et al . Birch pollen-related foods trigger atopic dermatitis in patients with specific cutaneous T-cell responses to birch pollen antigens. J Allergy Clin Immunol. 1999; 104 466-472
- 34 Östblom E, Lilja G, Ahlstedt S. et al . Patterns of antigen-specific IgE-antibodies and reported food hypersensitivity in 4-year-old children. Allergy. 2008; 63 418-424
- 35 Akdis M, Akdis C A. Mechanisms of allergen-specific immunotherapy. J Allergy Clin Immunol. 2007; 119 780-789
- 36 Akdis M, Verhagen A, Taylor A. Immune responses in healthy and allergic indiviguals are characterized by a fine balance between allergenspecific T regulatory and T helper 2 cells. J Exp Med. 2004; 199 1567-1575
- 37 Akdis M, Blaser K, Akdis C A. T regulatory cells in allergy: Novel concepts in the pathogenesis, prevention, and treatment of allergic diseases. J Allergy Clin Immunol. 2005; 116 961-968
- 38 Bieber T. The pro- and anti-inflammatory properties of human antigen-presenting cells expressing the high affinity receptor for IgE (Fc epsilon RI). Immunobiology. 2007; 212 499-503
- 39 Akdis C A, Akdis M, Bieber T. et al . Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergy, Asthma and Immunology/PRACTALL Consensus report. J Allergy Clin Immunol. 2006; 118 152-169
- 40 Jonuleit H, Schmitt E, Schuler G. et al . Induction of Interleukin-10-producing, non-proliferating CD4+ T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med. 2000; 192 1213-1222
- 41 Jutel M, Akdis M, Budak F. et al . IL-10 and TGF-β cooperate in regulatory T cell response to mucosal allergens in normal immunity and specific immunotherapy. Eur J Immunol. 2003; 33 1205-1214
- 42 Kapp A. Atopic dermatitis-the skin manifestation of atopy. Clin Exp Allergy. 1995; 25 210-219
- 43 Marshall J S, Leal-Berumen I, Nielsen L. et al . Interleukin (IL)-10 inhibits long-term IL-6 production but not preformed mediator release from rat peritoneal mast cells. J Clin Invest. 1996; 97 1122-1128
- 44 Novak N, Bieber T, Kraft S. Immunglobulin E-bearing antigen-presenting cells in atopic dermatitis. Curr Allergy Asthma Rep. 2004; 4 263-269
- 45 Schandane L, Alonso-Vega C, Willems F. et al . B7/CD28-dependent IL-5 production by human resting T cells is inhibited by IL-10. J Immunol. 1994; 152 4368-4374
- 46 Werfel T, Morita A, Grewe M. et al . Allergen specificity of skin infiltrating T cells is not restricted to a type 2 cytokine pattern in chronic skin lesions of atopic dermatitis. J Invest Dermatol. 1996; 107 871-876
- 47 Werfel T, Kapp A. Environmental and other major provocation factors in atopic dermatitis. Allergy. 1998; 53 731-739
- 48 Saarinen K M, Pelkonen A S, Makela M J. et al . Clinical course and prognosis of cow's milk allergy are dependent on milk-specific IgE status. J Allergy Clin Immunol. 2005; 116 869-875
- 49 American College of Allergy Asthma & Immunology . Food allergy: a practice parameter. Ann Allergy Asthma Immunol. 2006; 96 1-43
- 50 Novak N. Allergen specific immunotherapy for atopic dermatitis. J Allerg Clin Immunol. 2007; 7 542-546
- 51 Hanifin J M, Rajka G. Diagnstic features of atopic dermatitis. Acta Derm Venereol (Stockh). 1980; Suppl 92 44-47
- 52 Williams H C, Burney P G, Pembroke A C. et al . The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. III. Independent hospital validation. Br J Dermatol. 1994; 131 406-416
- 53 Tan B B, Weald D, Strickland I. et al . Double-blind controlled trial of effect of house-dust mite allergen avoidance on atopic dermatitis. Lancet. 1996; 347 15-18
- 54 Werfel T, Erdmann S, Fuchs T. et al . Leitlinie Vorgehen bei vermuteter Nahrungsmittelallergie bei atopischer Dermatitis. Allergologie. 2008; 31 333-342
- 55 Heine G, Schnuch A, Uter W. et al . Type-IV sensitization profile of individuals with atopic eczema: results from the Information Network of Departments of Dermatology (IVDK) and the German Contact Dermatitis Research Group (DKG). Allergy. 2006; 61 611-616
-
56 Werfel T, Aberer W, Augustin M. et al .Leitlinie Neurodermitis. AWMF Reg.-Nr. 013/027. AWMF online 2008.
- 57 Sampson H A. Utility of food-specific IgE concentrations in predicting symptomatic food allergy. J Allergy Clin Immunol. 2001; 107 891-896
- 58 Schäfer T, Stieger B, Polzius R. et al . Atopic eczema and indoor climate: results from the children from Lübeck allergy and environment study (KLAUS). Allergy. 2008; 63 244-246
- 59 Niebuhr M, Mai U, Kapp A. et al . Antibiotic treatment of cutaneous infections with Staphylococcus aureus in patients with atopic dermatitis: current antimicrobial resistances and susceptibilities. Exp Dermatol. 2008; 17 953-957
- 60 Lintu P, Savolainen J, Kortekangas-Savolainen O. et al . Systemic ketoconazole is an effective treatment of atopic dermatitis with IgE mediated hypersensitivity to yeasts. Allergy. 2001; 56 512-517
- 61 Mayser P, Kupfer J, Nemetz D. et al . Treatment of head and neck dermatitis with ciclopiroxolamine cream – results of a double-blind, placebo-controlled study. Skin Pharmacol Physiol. 2006; 19 153-158
- 62 Diepgen T L, Fartasch M, Ring J. et al . Education programs on atopic eczema. Design and first results of the German Randomized Intervention Multicenter Study. Hautarzt. 2003; 54 946-951
- 63 Staab D, Diepgen T L, Fartasch M. et al . Age related, structured educational programmes for the management of atopic dermatitis in children and adolescents: multicentre, randomised controlled trial. BMJ. 2006; 332 933-938
- 64 Werfel T, Lotte C, Scheewe S, Staab D (Hrsg). Manual Neurodermitisschulung. München-Orlando; Dustri-Verlag 2008
Dr. med. Margarete Niebuhr
Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie der Medizinischen Hochschule Hannover
Ricklinger Straße 5
30449 Hannover
Email: niebuhr.margarete@mh-hannover.de