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Exp Clin Endocrinol Diabetes 1983; 82(4): 42-50
DOI: 10.1055/s-0029-1210254
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Influence of Lesions of the Limbic-Hypothalamic System on Adrenocortical Responses to Daily Repeated Heat Exposures in Rabbits

K. Seto, H. Kaba, H. Saito, N. Edashige, M. Kawakami†
  • First Department of Physiology (Chairman: Prof. Dr. E. Seto) Kochi Medical School, Nankoku, Department of Medical Technology (Chairman: Prof. Dr. S. Sato) Kochi Gakuen College, Kochi and Second Department of Physiology (Chairman: Prof. Dr. M. Kawakami†) Yokohama City University School of Medicine, Yokohama/Japan
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Publication History

1982

Publication Date:
17 July 2009 (online)

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Summary

The effects of lesions in the basal medial hypothalamus and limbic structure upon the responses of adrenocorticoids formation in adrenal slices of rabbits to daily repeated heat exposures has been investigated. (1) The adrenocortical responses to heat exposure on the 1st day were decreased by lesions in the periventricular arcuate nucleus (ARC), ventromedial hypothalamus (VMH), stria terminalis (ST) and dorsal fornix (FX). (2) There were no effects of heat exposure on the 10 th day upon the adrenocorticoid formation in either the sham-lesioned rabbits or the rabbits with the lesions of ARC, VMH and ST. (3) In rabbits with the FX lesions, the adrenocorticoids formation was significantly increased by heat exposure on the 10 th day. (4) These results suggested that the basal medial hypothalamus, amygdala (AMYG)-ST system and dorsal hippocampus (HPC)-FX system participated in the mechanisms of adrenocortical responses to heat exposure on the 1st day, but only the HPC-FX system played some roles in complete disappearance process of adrenocortical responses to heat exposure by repetition of exposures.

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