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Exp Clin Endocrinol Diabetes 1983; 82(4): 101-103
DOI: 10.1055/s-0029-1210262
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Verapamil Increases Adrenocortical Secretory Reserve

I. Žofková, J. Blahoš, M. Neradilová, L. Stárka
  • Research Institute of Endocrinology, (Director: MUDr. J. Pečeny, CSc), Prague and Medical Clinic (Head: Prof. MUDr. Z. Svoboda, DrSc) Faculty of Pediatrics, Charles University, Prague/Czechoslovakia
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Publication History

1982

Publication Date:
17 July 2009 (online)

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Summary

The authors investigated the effect of commonly used therapeutic doses of calcium antagonist verapamil on the resting cortisol level and on the adrenocortical secretory reserve assessed from the response of cortisol blood level to stimulation with ACTH in 20 healthy subjects. Verapamil increased significantly the adrenocortical secretory reserve. The resting cortisol blood levels were not affected by the investigated substance. The authors discuss the possible practical impact of the assembled findings.

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