Prolonged Influence of a Single Neonatal Steroid (Dexamethasone) Treatment on Thymocytic Steroid Binding

Ágnes Inczefi-Gonda; G. Csaba

doi:10.1055/s-0029-1210462

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Exp Clin Endocrinol Diabetes 1985; 85(3): 358-360
DOI: 10.1055/s-0029-1210462

Short Communication

Prolonged Influence of a Single Neonatal Steroid (Dexamethasone) Treatment on Thymocytic Steroid Binding

Ágnes Inczefi-Gonda, G. Csaba

Department of Biology, Semmelweis University of Medicine Budapest/Hungary

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Publikationsverlauf

1984

Publikationsdatum:
16. Juli 2009 (online)

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Summary

Treatment of newborn rats with a single low dose of dexamethasone gave rise to lasting alteration of thymocytic receptor binding capacity. The receptors decreased markedly in number, while their affinity for the hormone was slightly increased. It appears that imprinting with a steroid changes the receptor — hormone relationship in the adult organism.

Key words

Dexamethasone - Imprinting - Thymocytic receptor