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Exp Clin Endocrinol Diabetes 1985; 85(3): 358-360
DOI: 10.1055/s-0029-1210462
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© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Prolonged Influence of a Single Neonatal Steroid (Dexamethasone) Treatment on Thymocytic Steroid Binding

Ágnes Inczefi-Gonda, G. Csaba
  • Department of Biology, Semmelweis University of Medicine Budapest/Hungary
Further Information

Publication History

1984

Publication Date:
16 July 2009 (online)

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Summary

Treatment of newborn rats with a single low dose of dexamethasone gave rise to lasting alteration of thymocytic receptor binding capacity. The receptors decreased markedly in number, while their affinity for the hormone was slightly increased. It appears that imprinting with a steroid changes the receptor — hormone relationship in the adult organism.

Key words

Dexamethasone - Imprinting - Thymocytic receptor