PDF icon PDF herunterladen
Exp Clin Endocrinol Diabetes 1988; 91(1): 123-126
DOI: 10.1055/s-0029-1210733
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Influence of Microinjection of Corticosterone into Hippocampus on Hepatic Acetate Metabolism in Rabbits

K. Seto, H. Saito, H. Kaba, A. Ohri, K. Nojima, T. Takahashi1) , A. Tamai1) , M. Kawakami2)
  • 1First Department of Physiology (Chairman: Prof. Dr. K. Seto), and Department of Opthalmology (Chairman: Prof. Dr. A. Tamai), Kochi Medical School, Nankoku/Japan
  • 2Second Department of Physiology (Former Chairman: Prof. Dr. M. Kawakami), Yokohama City University School of Medicine, Yokohama/Japan
Weitere Informationen

Publikationsverlauf

1987

Publikationsdatum:
16. Juli 2009 (online)

Auch verfügbar aufeRef
 als PDF herunterladen  Lizenzen und Reprints
Preview

Summary

Corticosterone was injected directly into the hippocampus of rabbits, and changes in hepatic acetate metabolism were studied. The microinjection of corticosterone with seasame oil into hippocampus decreased the rates of 14C transfer from 14C-1-acetate into CO2 and free cholesterol, and increased 14C transfer into glucose, ketone bodies, triglyceride, free fatty acids and phospholipids. But after microinjection of corticosterone into the hippocampus of rabbits with lesions of dorsal fornix, hepatic acetate metabolism did not differ from that of control rabbits, which received injection of seasame oil into the same brain region. From these results it might be suggested that the hippocampus is a part of corticosterone-sensitive brain regulator system in the hepatic acetate metabolism.

Key words

Corticosterone - Acetate Metabolism - Hippocampus - Rabbits