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Exp Clin Endocrinol Diabetes 1988; 91(2): 241-243
DOI: 10.1055/s-0029-1210754
Short Communication

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Influence of Bleeding Order on Plasma Corticosterone Concentration in the Mouse

J. Kugler, K. W. Lange, K. Th. Kalveram
  • Section of Psychological Cybernetics and Psychobiology, Institute of Psychology I (Head: Prof. Dr. K. Th. Kalveram), University of Düsseldorf/F.R.G.
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Publikationsverlauf

1987

Publikationsdatum:
16. Juli 2009 (online)

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Summary

The influence of the order of bleeding on corticosterone release in the mouse was examined. Female C57/BL6 mice were housed in groups of five animals in a low noise environment. After 10 days, they were successively captured and sacrificed every 2 minutes. The corticosterone levels increased in the fourth and fifth mice in a cage, i.e. within the time intervals from 4 to 6 minutes and from 6 to 8 minutes after the capture of the first animal. These results suggest that quiescent corticosterone levels can be measured only when the blood samples are obtained within 4 minutes following the capture of the first mouse.

Key words

Corticosterone - Bleeding procedure - Mouse - Stress