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Exp Clin Endocrinol Diabetes 1988; 92(5): 241-244
DOI: 10.1055/s-0029-1210809
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Effects of Ovine Prolactin in Infant Rats

A. Ryníková, J. Koppel, S. Kuchár, Š. Čikoš, Š. Mozeš
  • Institute of Animal Physiology (Head: Academician K. Boďa) Slovak Academy of Sciences, Kosice/Czechoslovakia
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Publikationsverlauf

1988

Publikationsdatum:
16. Juli 2009 (online)

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Summary

The objective of this study was to determine the effects of ovine prolactin (oPRL) on body growth and the content of UNA, DNA and protein in liver, brain and heart muscle in rat pups. Suckling rats were daily injected from 3rd to 28th day of life with 1 μg of oPRL/g body weight. Our results show that oPRL administration evoked higher body weight gain up to 8th day of life (p < 0.05). There was significant (p < 0.05) increase of DNA liver content and significant decrease (p < 0.001) of RNA/DNA ratio in the hepatocytes. The findings suggest that prolactin influences growth rate of rats in the early postnatal period of life.

Key words

oPRL - Rat pups - Body growth