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Exp Clin Endocrinol Diabetes 1989; 94(4/05): 177-186
DOI: 10.1055/s-0029-1210895
Original

© J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Pituitary Response in the Doubled GnRH-TRH Test on the 5th Day Post Partum or Post Abortum after Ablactation by Oral Means of Ethinylestradiol Sulfonate*)

G. Göretzlehner, W. Wodrig, Andra Leminski, A. Weber, U. Ulrich
  • Department of Obstetrics and Gynecology of the Ernst-Moritz-Arndt-University, Greifswald, DDR
*) Dedicated to Professor Dr. G. Dörner on the occasion of his 60th birthday.
Further Information

Publication History

1988

Publication Date:
16 July 2009 (online)

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Summary

The function and reactivity of the hypothalamo — anterior pituitary axis had been tested after primary ablactation with ethinylestradiol sulfonate (EES) by means of the doubled GnRH-TRH-test. The reaction of the hypothalamo-pituitary axis is, in early puerperium, drastically reduced by GnRH stimulation. The physiological hyperprolactinemia of puerperium leads to a non-responsiveness by means of exogenous GnRH. Simultaneously there exists a greater sensitivity of the hypothalamo-pituitary system for the negative and a relatively lesser sensitivity for the positive feedback of estrogens in puerperium.

Key words

Doubled GnRH-TRH test - Ethinylestradiol sulfonate - LH - FSH - PRL - TSH

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