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Semin Respir Crit Care Med 2009; 30(5): 559-568
DOI: 10.1055/s-0029-1238914
© Thieme Medical PublishersDOI: 10.1055/s-0029-1238914
Lung Transplantation in Patients with Cystic Fibrosis
Further Information
Publication History
Publication Date:
16 September 2009 (online)
ABSTRACT
Cystic fibrosis is one of the most common indications for lung transplantation worldwide and certainly the most common indication for all pediatric lung transplants and for bilateral lung transplantation irrespective of age. Outcomes are outstanding when compared with other indications for lung transplantation, and an increasing number of centers now report mean survival of greater than 10 years posttransplant. Hence it is important to concentrate on the broad panoply of potential systemic complications of cystic fibrosis and address proactively issues that may be associated with adverse outcomes. Optimum management of infectious, nutritional, diabetic, renal, bone, and gut complications is critical to long-term success so that recipients may realize their full potential. Timing of referral for consideration of active listing should allow sufficient time for the patient and lung transplant team to develop a productive working relationship based on best available evidence and mutual trust, which will culminate in a long-term successful outcome.
KEYWORDS
Cystic fibrosis - lung transplantation
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Allan R GlanvilleM.D.
The Lung Transplant Unit, Xavier 4, St. Vincent's Hospital
Victoria St., Darlinghurst NSW, Australia 2010
Email: aglanville@stvincents.com.au