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Int J Sports Med 2010; 31(5): 298-303
DOI: 10.1055/s-0030-1248321
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Influence of Blood Donation on Oxygen Uptake Kinetics During Moderate and Heavy Intensity Cycle Exercise

D. Gordon1 , K. Marshall2 , A. Connell2 , R. J. Barnes2
  • 1Anglia Ruskin University, Life Sciences, Cambridge, United Kingdom
  • 2Cambridge University, Physiology Development and Neuroscience, Cambridge, United Kingdom
Further Information

Publication History

accepted after revision January 19, 2010

Publication Date:
23 February 2010 (online)

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Abstract

The purpose of this study was to determine the effects of a reduced whole body blood volume on the kinetic response of VO2 during moderate and heavy intensity exercise. Six males and four females (age, 21±2 yrs; height, 175.2±5.1 cm; weight, 66.4±2.8 kg; VO2max, 53.0±4.1 ml.kg−1.min−1), completed a square-wave cycling ramp test to determine ventilatory threshold (VT) and VO2max. Kinetics trials were completed 24 h pre and post donation of 450 cm3 of blood. The kinetics trials were moderate intensity (80%VT) and heavy intensity (Δ50% VT – VO2max). Breath-by-breath gas exchange, heart rate, blood pressure, haemoglobin O2 saturation, and blood [lactate] were measured throughout the trials. Post-donation haemoglobin, haematocrit and erythrocyte count were all significantly reduced (p≤ 0.05). Blood donation caused a significant increase in resting heart rate (P≤ 0.05). There were non-significant differences in the time constants or amplitude of phase II VO2 kinetics in either moderate or heavy exercise (p≥ 0.05), or in the amplitude of the slow component. The capacity of the cardiovascular system to meet the metabolic demands of skeletal muscle at the onset of exercise does not limit the oxygen uptake.

Key words

supply and demand - on-transit kinetics - circulation

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Correspondence

Dan Gordon

Anglia Ruskin University Life Sciences

Unit for Sport and Exercise Sciences

CB1 1PT Cambridge

United Kingdom

Phone: +44/845 1962774

Fax: +44/1223 417712

Email: dan.gordon@anglia.ac.uk

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