Int J Sports Med 2011; 32(5): 327-331
DOI: 10.1055/s-0030-1263138
Physiology & Biochemistry

© Georg Thieme Verlag KG Stuttgart · New York

Cardiac Biomarker Response to Intermittent Exercise Bouts

L. E. Carranza-García1 , K. George2 , E. Serrano-Ostáriz3 , R. Casado-Arroyo4 , A. L. Caballero-Navarro1 , A. Legaz-Arrese1
  • 1University of Zaragoza, Section of Physical Education and Sports, Zaragoza, Spain
  • 2Liverpool John Moores University, Sport and Exercise Science, Liverpool, United Kingdom
  • 3Universidad de Zaragoza, Fisiatría y Enfermería, Zaragoza, Spain
  • 4Lozano Blesa Universitary Clinic Hospital, Service of Cardiology, Zaragoza, Spain
Further Information

Publication History

accepted after revision July 20, 2010

Publication Date:
05 May 2011 (online)


The impact of intermittent exercise on cardiac biomarker release has not been clearly established. In experienced athletes, we examined the acute effect of a heavy resistance training session (n=18 males) and an indoor soccer match (n=21, 11 males, 10 females) on the release of cTnI, cTnT, and NT-proBNP. Biomarkers were assayed from blood samples collected at rest, immediately post- and at 1, 3, 6, 12, and 24 h post-exercise. The heavy resistance training session resulted in an increase in NT-proBNP (pre: 15±17, peak post: 41±56 ng L−1; p=0.001) but not in cTnI (pre: 0.024±0.009, peak post: 0.025±0.011 μg L−1, p=0.809) or cTnT (undetectable in all samples). The indoor soccer match led to an increase in the release of NT-proBNP (pre: 28±32, peak post: 66±56 ng L−1; p=0.000) and cTnI (pre: 0.026±0.047, peak post: 0.033±0.051 μg L−1; p=0.008) in both males and females but not cTnT (detectable in only one subject). The current data suggest that intermittent bouts of exercise result in only modest perturbations of cardiac biomarkers with very limited evidence of myocyte injury/insult.


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Dr. Luis Enrique Carranza-García

University of Zaragoza

Section of Physical Education

and Sports

C/Domingo Miral S/N

50009 Zaragoza


Phone: +34/976/76 17 19

Fax: +34/976/76 17 20