Semin Musculoskelet Radiol 2010; 14(5): 463-472
DOI: 10.1055/s-0030-1268067
© Thieme Medical Publishers

Ultrasound and Magnetic Resonance Imaging of the Peripheral Nerves: Current Techniques, Promising Directions, and Open Issues

Erwan Kermarrec1 , Xavier Demondion1 , Chadi Khalil1 , Vianney Le Thuc1 , Nathalie Boutry1 , Anne Cotten1
  • 1Service de Radiologie et Imagerie Musculosquelettique, Centre de Consultation et d'Imagerie de l'Appareil Locomoteur, CHRU de Lille, France
Further Information

Publication History

Publication Date:
11 November 2010 (online)

ABSTRACT

High-resolution ultrasound (US) and magnetic resonance (MR) imaging are the two imaging methods of choice for the study of peripheral nerves. The many advances that have been made in recent years, either by US or MR imaging, including diffusion tensor imaging and tractography, offer new perspectives for the assessment of many pathological processes affecting peripheral nerves such as entrapment syndromes, tumors and tumor-like lesions, and traumatic disorders. Most of these improvements have especially increased the spatial resolution of nerve imaging. US and MR imaging are complementary, each having advantages and disadvantages. Tractography is still emerging in the musculoskeletal field, particularly for the analysis of peripheral nerves, but this technique seems promising.

REFERENCES

  • 1 Beekman R, Visser L H. High-resolution sonography of the peripheral nervous system—a review of the literature.  Eur J Neurol. 2004;  11(5) 305-314
  • 2 Bianchi S. Ultrasound of the peripheral nerves.  Joint Bone Spine. 2008;  75(6) 643-649
  • 3 Silvestri E, Martinoli C, Derchi L E, Bertolotto M, Chiaramondia M, Rosenberg I. Echotexture of peripheral nerves: correlation between US and histologic findings and criteria to differentiate tendons.  Radiology. 1995;  197(1) 291-296
  • 4 Fornage B D. Peripheral nerves of the extremities: imaging with US.  Radiology. 1988;  167(1) 179-182
  • 5 Gruber H, Glodny B, Bendix N, Tzankov A, Peer S. High-resolution ultrasound of peripheral neurogenic tumors.  Eur Radiol. 2007;  17(11) 2880-2888
  • 6 Filler A G, Kliot M, Howe F A et al.. Application of magnetic resonance neurography in the evaluation of patients with peripheral nerve pathology.  J Neurosurg. 1996;  85(2) 299-309
  • 7 Filler A G, Howe F A, Hayes C E et al.. Magnetic resonance neurography.  Lancet. 1993;  341(8846) 659-661
  • 8 Filler A G, Maravilla K R, Tsuruda J S. MR neurography and muscle MR imaging for image diagnosis of disorders affecting the peripheral nerves and musculature.  Neurol Clin. 2004;  22(3) 643-682, vi–vii
  • 9 Howe F A, Filler A G, Bell B A, Griffiths J R. Magnetic resonance neurography.  Magn Reson Med. 1992;  28(2) 328-338
  • 10 Aagaard B D, Maravilla K R, Kliot M. Magnetic resonance neurography: magnetic resonance imaging of peripheral nerves.  Neuroimaging Clin N Am. 2001;  11(1) viii, 131-146
  • 11 Khalil C, Hancart C, Le Thuc V, Chantelot C, Chechin D, Cotten A. Diffusion tensor imaging and tractography of the median nerve in carpal tunnel syndrome: preliminary results.  Eur Radiol. 2008;  18(10) 2283-2291
  • 12 Hiltunen J, Suortti T, Arvela S, Seppä M, Joensuu R, Hari R. Diffusion tensor imaging and tractography of distal peripheral nerves at 3 T.  Clin Neurophysiol. 2005;  116(10) 2315-2323
  • 13 Skorpil M, Karlsson M, Nordell A. Peripheral nerve diffusion tensor imaging.  Magn Reson Imaging. 2004;  22(5) 743-745
  • 14 Takagi T, Nakamura M, Yamada M et al.. Visualization of peripheral nerve degeneration and regeneration: monitoring with diffusion tensor tractography.  Neuroimage. 2009;  44(3) 884-892
  • 15 Kabakci N, Gürses B, Firat Z et al.. Diffusion tensor imaging and tractography of median nerve: normative diffusion values.  AJR Am J Roentgenol. 2007;  189(4) 923-927
  • 16 Koenig R W, Pedro M T, Heinen C P et al.. High-resolution ultrasonography in evaluating peripheral nerve entrapment and trauma.  Neurosurg Focus. 2009;  26(2) E13
  • 17 Kim S, Choi J Y, Huh Y M et al.. Role of magnetic resonance imaging in entrapment and compressive neuropathy—what, where, and how to see the peripheral nerves on the musculoskeletal magnetic resonance image: part 2. Upper extremity.  Eur Radiol. 2007;  17(2) 509-522
  • 18 Martinoli C, Bianchi S, Gandolfo N, Valle M, Simonetti S, Derchi L E. US of nerve entrapments in osteofibrous tunnels of the upper and lower limbs.  Radiographics. 2000;  20(Spec No) S199-S213 discussion S213-S217
  • 19 Maravilla K R, Bowen B C. Imaging of the peripheral nervous system: evaluation of peripheral neuropathy and plexopathy.  AJNR Am J Neuroradiol. 1998;  19(6) 1011-1023
  • 20 Stolinski C. Structure and composition of the outer connective tissue sheaths of peripheral nerve.  J Anat. 1995;  186(Pt 1) 123-130
  • 21 Lundborg G. Intraneural microcirculation.  Orthop Clin North Am. 1988;  19(1) 1-12
  • 22 Stuart R M, Koh E S, Breidahl W H. Sonography of peripheral nerve pathology.  AJR Am J Roentgenol. 2004;  182(1) 123-129
  • 23 Lin D C, Nazarian L N, O'Kane P L, McShane J M, Parker L, Merritt C R. Advantages of real-time spatial compound sonography of the musculoskeletal system versus conventional sonography.  AJR Am J Roentgenol. 2002;  179(6) 1629-1631
  • 24 Klauser A S, Peetrons P. Developments in musculoskeletal ultrasound and clinical applications.  Skeletal Radiol. 2009;  , September 3 (Epub ahead of print)
  • 25 Claudon M, Tranquart F, Evans D H, Lefèvre F, Correas M. Advances in ultrasound.  Eur Radiol. 2002;  12(1) 7-18
  • 26 Martinoli C, Bianchi S, Dahmane M, Pugliese F, Bianchi-Zamorani M P, Valle M. Ultrasound of tendons and nerves.  Eur Radiol. 2002;  12(1) 44-55
  • 27 Martinoli C, Derchi L E, Bertolotto M et al.. US and MR imaging of peripheral nerves in leprosy.  Skeletal Radiol. 2000;  29(3) 142-150
  • 28 Barberie J E, Wong A D, Cooperberg P L, Carson B W. Extended field-of-view sonography in musculoskeletal disorders.  AJR Am J Roentgenol. 1998;  171(3) 751-757
  • 29 Cooperberg P L, Barberie J J, Wong T, Fix C. Extended field-of-view ultrasound.  Semin Ultrasound CT MR. 2001;  22(1) 65-77
  • 30 Kim S, Choi J Y, Huh Y M et al.. Role of magnetic resonance imaging in entrapment and compressive neuropathy—what, where, and how to see the peripheral nerves on the musculoskeletal magnetic resonance image: part 1. Overview and lower extremity.  Eur Radiol. 2007;  17(1) 139-149
  • 31 Wong B Z, Amrami K K, Wenger D E, Dyck P J, Scheithauer B W, Spinner R J. Lipomatosis of the sciatic nerve: typical and atypical MRI features.  Skeletal Radiol. 2006;  35(3) 180-184
  • 32 Moore K R, Tsuruda J S, Dailey A T. The value of MR neurography for evaluating extraspinal neuropathic leg pain: a pictorial essay.  AJNR Am J Neuroradiol. 2001;  22(4) 786-794
  • 33 Dailey A T, Tsuruda J S, Filler A G, Maravilla K R, Goodkin R, Kliot M. Magnetic resonance neurography of peripheral nerve degeneration and regeneration.  Lancet. 1997;  350(9086) 1221-1222
  • 34 Chappell K E, Robson M D, Stonebridge-Foster A et al.. Magic angle effects in MR neurography.  AJNR Am J Neuroradiol. 2004;  25(3) 431-440
  • 35 Kamath S, Venkatanarasimha N, Walsh M A, Hughes P M. MRI appearance of muscle denervation.  Skeletal Radiol. 2008;  37(5) 397-404
  • 36 Holl N, Echaniz-Laguna A, Bierry G et al.. Diffusion-weighted MRI of denervated muscle: a clinical and experimental study.  Skeletal Radiol. 2008;  37(12) 1111-1117
  • 37 Mori S, Crain B J, Chacko V P, van Zijl P C. Three-dimensional tracking of axonal projections in the brain by magnetic resonance imaging.  Ann Neurol. 1999;  45(2) 265-269
  • 38 Merlini L, Viallon M, De Coulon G, Lobrinus J A, Vargas M I. MRI neurography and diffusion tensor imaging of a sciatic perineuroma in a child.  Pediatr Radiol. 2008;  38(9) 1009-1012

Erwan KermarrecM.D. 

Service de Radiologie et Imagerie Musculosquelettique, Centre de Consultation et d'Imagerie de l'Appareil Locomoteur

CHRU de Lille, 59037 France

Email: erwankermarrec@yahoo.fr

    >