Int J Angiol 2007; 16(3): 113-114
DOI: 10.1055/s-0031-1278261
Case Reports

© Georg Thieme Verlag KG Stuttgart · New York

Sarcoidosis, microvascular angina and aortitis: New dimensions of the 'Takayasu syndrome' -A case report

Isma Rafiq, Vidya Nadig, Leisa J Freeman
  • Department of Cardiology, Norfolk and Norwich University NHS Trust, Norwich, United Kingdom
Further Information

Publication History

Publication Date:
27 April 2011 (online)


A case of Takayasu aortitis associated with sarcoidosis presenting with recurrent angina is reported. This association has been called 'Takayasu syndrome', which reflects what is likely a shared etiology. Myocardial perfusion abnormalities have recently been documented in sarcoidosis, but this case clarifies for the first time that the angina in Takayasu syndrome is likely due to small vessel coronary arteritis. Corticosteroids and cytotoxic therapy have been shown to be beneficial in all forms of sarcoidosis related to vasculitis. Initiation of steroid therapy may provide relief of angina in patients with evidence of reversible ischemia in normal coronary arteries.