ABSTRACT
The aim of this study was to establish an objective evaluation method for intraoperative
detection of damaged vascular endothelium in avulsion injuries. Twenty male Fischer
rats were randomly assigned to control or experimental groups (n = 10, each). Crush-avulsion injury was performed on right femoral arteries. Resection
of damaged segments was performed according to operative microscopic findings in the
control group; fluorescein sodium was applied to the artery lumen before resection
in the experimental group to help visualize the damaged endothelium. Microvascular
repair was performed in five rats in each group. In the other animals, the whole length
of the femoral arteries was resected to assess the actual extent of injury histologically.
At the end of the follow-up period, patency of microvascular anastomoses was examined
and the lengths of the resected segments were compared with the actual length of the
injured segment measured histologically. The difference between these two measurements
was statistically significant in the control group (p < 0.05) but not in the experimental group (p > 0.05). Anastomosis patency was significantly higher in the experimental group (p < 0.0001). In conclusion, fluorescein sodium may help to accurately determine the
length of the injured vascular segment in avulsion injuries.
KEYWORDS
Microsurgery - fluorescence - avulsion
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Muhammet UraloğluM.D.
Karadeniz Teknik Üniversitesi Tip Fakültesi
Farabi Hastanesi Plastik Cerrahi Anabilim Dali, Trabzon, Turkey
Email: uraloglu@hotmail.com
