Geburtshilfe Frauenheilkd 2011; 71 - O_15
DOI: 10.1055/s-0031-1286470

Trophoblasttumorregister der Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) – erste Ergebnisse:

LC Horn 1
  • 1Institute of Pathology, Division of Breast, Gynecologic & Perinatal Pathology, University of Leipzig

Fragestellung:

Gestational trophoblastic disease (GTD) includes a wide range of morphologic different lesions with divergent clinical behaviour. The exact number of cases and the incidence is not known for Germany. Cancer registries will cover only choriocarcinomas and in case of malignant course the placental site and the epitheloid trophoblastic tumor.

Methode:

The German Working Group for Gynecologic Malignancies (Arbeitsgemeinschaft für Gynäkologische Onkologie e.V. (AGO) which acts under the roof of the German Cancer Society and the German Society of Obstetrics and Gynecology has established a registry for GTD for two years. Registered cases and previous ones collected at the University of Leipzig since 1996 were evaluated.

Ergebnisse:

65 cases were available. These included 16.4% partial mole, 8.8% complete moles, and 1.2% for the villous forms of GTD and 18.1% exaggerated placantal sites, 14.6% placental site nodules, 2.9% choriocarcinomas and 2.4% placental site trophoblastic tumors.

Schlussfolgerung:

The villous forms of GTD are the most prevalent ones. The registry allows the collection of large number of cases which might subject of molecular studies.