Minim Invasive Neurosurg 2011; 54(05/06): 268-270
DOI: 10.1055/s-0031-1297989
Case Report
© Georg Thieme Verlag KG Stuttgart · New York

Stereotactic Brainstem Biopsy in a Patient with Coagulopathy of Unclear Etiology: Case Report

C. Beynon1, T. Hoffmann2, W. Wick3, A. W. Unterberg1, K. L. Kiening1, 4
  • 1Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany
  • 2Institute of Hemostasis and Transfusion Medicine, University Hospital of Düsseldorf, Düsseldorf, Germany
  • 3Department of Neurooncology, Heidelberg University Hospital, Heidelberg, Germany
  • 4Division of Stereotactic Neurosurgery, Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany
Further Information

Publication History

Publication Date:
25 January 2012 (online)



Parenchymal hemorrhage is one of the most feared risks of stereotactic brain biopsies potentially resulting in neurological deficits or even a fatal outcome. Patients with disorders of the coagulation system are at particular risk, so identifying these is one of the main tasks prior to surgery. Some patients may have a bleeding tendency despite normal laboratory values of the hemostatic system.

Case Report:

We report the case of a patient with coagulopathy of unclear etiology undergoing a stereotactic brainstem biopsy.


A medication scheme with tranexamic acid and desmopressin effectively decreased the patient’s bleeding time in vivo and the procedure was carried out without complications.