Facial Plast Surg 2011; 27(6): 523-528
DOI: 10.1055/s-0031-1298785
© Thieme Medical Publishers

Hyaluronic Acid Fillers: History and Overview

Ji-Eon Kim1 , Jonathan M. Sykes1
  • 1Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology–Head and Neck Surgery, University of California, Davis, Sacramento, California
Further Information

Publication History

Publication Date:
28 December 2011 (online)


Hyaluronic acid (HA) fillers have many favorable characteristics that make it a popular injectable filler device. Its minimal immunogenicity and relative ease of use has helped HA become the most commonly used injectable filler today. A brief history of injectable fillers, the various injection techniques, and legal ramifications are discussed. A review of the most recent literature compares the efficacy and safety of HA to other injectable filler substances.


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Jonathan M. SykesM.D. 

Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology–Head and Neck Surgery

2521 Stockton Blvd, Suite 6206, Sacramento, CA 95817

Email: jonathan.sykes@ucdmc.ucdavis.edu