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Semin Thromb Hemost 2012; 38(04): 333-338
DOI: 10.1055/s-0032-1304718
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Update on the Catastrophic Antiphospholipid Syndrome and the “CAPS Registry”

Ricard Cervera
1   Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Catalonia, Spain
,
Gerard Espinosa
1   Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Catalonia, Spain
› Author Affiliations
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Publication History

Publication Date:
05 March 2012 (online)

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Abstract

Although less than 1% of patients with the antiphospholipid syndrome (APS) develop the catastrophic variant known as catastrophic antiphospholipid syndrome (CAPS), its potentially lethal outcome emphasizes its importance in clinical medicine today. However, the rarity of this variant makes it extraordinarily difficult to study in any systematic way. To collate all the published case reports as well as the newly diagnosed cases from all over the world, an international registry of patients with CAPS (“CAPS Registry”) was created in 2000 by the European Forum on Antiphospholipid Antibodies (www.med.ub.es/MIMMUN/FORUM/CAPS.HTM). Currently, this database documents the entire clinical, laboratory, and therapeutic data of more than 350 fully registered patients.

Keywords

catastrophic antiphospholipid syndrome - Asherson syndrome - antiphospholipid antibodies - anticardiolipin antibodies - lupus anticoagulant - antiphospholipid syndrome
 

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