Int J Angiol 2012; 21(01): 059-062
DOI: 10.1055/s-0032-1306419
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

A Novel Technique in the Use of Fractional Flow Reserve in Coronary Artery Bifurcation Lesions

Justin A. Ratcliffe
1   Department of Cardiology, Albert Einstein College of Medicine, Beth Israel Medical Center, New York, New York
,
Yili Huang
1   Department of Cardiology, Albert Einstein College of Medicine, Beth Israel Medical Center, New York, New York
,
Tak Kwan
1   Department of Cardiology, Albert Einstein College of Medicine, Beth Israel Medical Center, New York, New York
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
03. März 2012 (online)

Abstract

The side branch (SB) in bifurcation lesions is a frequently encountered challenge that interventional cardiologists must face. There is great interest in determining fractional flow reserve (FFR) in the SB to help guide treatment decisions; however, difficulty with the pressure guidewire limits its widespread use. We propose a novel technique that will ease the incorporation of FFR in routine evaluation of bifurcation lesions, and allow better assessment of provisional stenting and need for SB intervention. Conventionally, to measure SB FFR, the jailed SB is re-crossed through the stent strut using a pressure wire. Our technique involves the use of a microcatheter and wire exchange within the SB, thereby alleviating some of the technical difficulties associated with the FFR wire. In light of the difficulties and clinical concerns associated with bifurcation lesions, we propose an innovative method to ease the incorporation of FFR to allow better assessment of provisional stenting and need for SB intervention.

 
  • References

  • 1 Iakovou I, Ge L, Colombo A. Contemporary stent treatment of coronary bifurcations. J Am Coll Cardiol 2005; 46 (8) 1446-1455
  • 2 Hildick-Smith D, de Belder AJ, Cooter N , et al. Randomized trial of simple versus complex drug-eluting stenting for bifurcation lesions: the British Bifurcation Coronary Study: old, new, and evolving strategies. Circulation 2010; 121 (10) 1235-1243
  • 3 Steigen TK, Maeng M, Wiseth R , et al; Nordic PCI Study Group. Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study. Circulation 2006; 114 (18) 1955-1961
  • 4 Ferenc M, Gick M, Kienzle R-P , et al. Randomized trial on routine vs. provisional T-stenting in the treatment of de novo coronary bifurcation lesions. Eur Heart J 2008; 29 (23) 2859-2867
  • 5 Colombo A, Bramucci E, Sacca S , et al. Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study. Circulation 2009; 119: 71-78
  • 6 Korn HV, Yu J, Ohlow MA , et al. Interventional therapy of bifurcation lesions: a TIMI flow-guided concept to treat side branches in bifurcation lesions—a prospective randomized clinical study (Thueringer bifurcation study, THUEBIS study as pilot trial). Circ Cardiovasc Interv 2009; 2 (6) 535-542
  • 7 Niemelä M, Kervinen K, Erglis A , et al; Nordic-Baltic PCI Study Group. Randomized comparison of final kissing balloon dilatation versus no final kissing balloon dilatation in patients with coronary bifurcation lesions treated with main vessel stenting: the Nordic-Baltic Bifurcation Study III. Circulation 2011; 123 (1) 79-86
  • 8 Tonino PA, De Bruyne B, Pijls NH , et al; FAME Study Investigators. Fractional flow reserve versus angiography for guiding percutaneous coronary intervention. N Engl J Med 2009; 360 (3) 213-224
  • 9 Koo BK, Kang HJ, Youn TJ , et al. Physiologic assessment of jailed side branch lesions using fractional flow reserve. J Am Coll Cardiol 2005; 46 (4) 633-637
  • 10 Koo BK, Park KW, Kang HJ , et al. Physiological evaluation of the provisional side-branch intervention strategy for bifurcation lesions using fractional flow reserve. Eur Heart J 2008; 29 (6) 726-732
  • 11 Koo BK, Waseda K, Kang HJ , et al. Anatomic and functional evaluation of bifurcation lesions undergoing percutaneous coronary intervention. Circ Cardiovasc Interv 2010; 3 (2) 113-119