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TumorDiagnostik & Therapie 2012; 33(7): 429-431
DOI: 10.1055/s-0032-1325418
Thieme Onkologie aktuell
© Georg Thieme Verlag KG Stuttgart · New York

Entzündungshemmende Medikamente und Prostatakarzinom: Aktueller Stand der Evidenz

Anti-Inflammatory Drugs and Prostatic Carcinoma: Current State of Evidence
H.-P. Schmid
1   Klinik für Urologie, Kantonsspital, St. Gallen
,
D. S. Engeler
1   Klinik für Urologie, Kantonsspital, St. Gallen
,
R. Theiler
2   Klinik für Rheumatologie, Stadtspital Triemli, Zürich
› Author Affiliations
Further Information

Publication History

Publication Date:
15 October 2012 (online)

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Zusammenfassung

Die epidemiologische Evidenz für einen protektiven Effekt von entzündungshemmenden Medikamenten gegen das Prostatakarzinom ist suggestiv aber nicht schlüssig beweisend. Studien dazu sind limitiert durch eine ungenügende Information über Dosierung und Dauer der Einnahme und durch methodische Verzerrungen. Zudem sollte ein möglicher Nutzen gegen die bekannten Nebenwirkungen bei Langzeitanwendung abgewogen werden.

Abstract

The epidemiological evidence for a protective effect of anti-inflammatory drugs against prostatic carcinoma is suggestive but not conclusive. Studies are limited by inadequate information on dose and duration of use and by methodological biases. Furthermore, potential benefits should be weighed against the known side effects of long-term use.

Schlüsselwörter

Prostatakarzinom - Entzündungen - nicht-steroidale Antirheumatika - Prävention

Key words

prostatic carcinoma - inflammation - non-steroidal anti-inflammatory drugs - prevention
 

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