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J Neurol Surg Rep 2012; 73(01): 001-005
DOI: 10.1055/s-0032-1329189
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Massive Transcranial Parotid Pleomorphic Adenoma: Recurrence after 30 Years[*]

Graham M. Strub
1   Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University Medical Center, Richmond, Virginia
,
Alexandros Georgolios
1   Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University Medical Center, Richmond, Virginia
,
Robert S. Graham
2   Department of Neurosurgery, Virginia Commonwealth University Medical Center, Richmond, Virginia
,
Celeste N. Powers
3   Department of Pathology, Virginia Commonwealth University Medical Center, Richmond, Virginia
,
Daniel H. Coelho
1   Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University Medical Center, Richmond, Virginia
› Author Affiliations
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Publication History

Publication Date:
21 September 2012 (online)

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Massive Transcranial Parotid Pleomorphic Adenoma: Recurrence after 30 YearsSkull Base Rep 2011; 01(S 01): e1-e1
DOI: 10.1055/s-0031-1296032

Abstract

Pleomorphic adenoma, also known as benign mixed tumor, is the most common tumor affecting the parotid gland and can reach massive size; however, intracranial invasion is rare. Recurrence of pleomorphic adenoma after excision is a well-known phenomenon and can present decades after resection of the primary tumor. Here we present the case of a 53-year-old man who presented to our clinic with ear fullness, otalgia, and hearing loss 30 years after undergoing total parotidectomy and external beam radiotherapy for pleomorphic adenoma. Magnetic resonance imaging revealed a massive transcranial tumor invading the mastoid cavity, the dura of the posterior fossa, the fallopian and semicircular canals, the jugular foramen, the lateral infratemporal fossa skull base, the sigmoid and transverse sinuses, and the superior parapharyngeal region. Gross examination and histopathological studies confirmed that the mass was a recurrent pleomorphic adenoma. Here we discuss the features of recurrent pleomorphic adenoma and review the current literature.

Keywords

pleomorphic adenoma - benign mixed tumor - recurrent pleomorphic adenoma - carcinoma ex pleomorphic adenoma - intracranial invasion

* This article was originally published in Skull Base Reports on November 21, 2011 (DOI: 10.1055/s-0031-1296032)


 

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