Semin Neurol 2012; 32(03): 187-195
DOI: 10.1055/s-0032-1329194
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Chronic Inflammatory Demyelinating Polyradiculoneuropathy: From Bench to Bedside

Amanda C. Peltier
1   Department of Neurology, Vanderbilt Medical Center, Medical Center North, Nashville, Tennessee
,
Peter D. Donofrio
1   Department of Neurology, Vanderbilt Medical Center, Medical Center North, Nashville, Tennessee
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
01. November 2012 (online)

Abstract

Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is the most common treatable chronic autoimmune neuropathy. Multiple diagnostic criteria have been established, with the primary goal of identifying neurophysiologic hallmarks of acquired demyelination. Treatment modalities have expanded to include numerous immunomodulatory therapies, although the best evidence continues to be for corticosteroids, plasma exchange, and intravenous immunoglobulin (IVIg). This review describes the pathology, epidemiology, pathogenesis, diagnosis, and treatment of CIDP.