Facial plast Surg 2012; 28(06): 545-553
DOI: 10.1055/s-0032-1329929
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Histopathology of Vascular Anomalies

Amir Aboutalebi1, Chad J. Jessup2, Paula E. North3, Martin C. Mihm Jr.4, 5
  • 1Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts
  • 2Department of Dermatology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts
  • 3Division of Pediatric Pathology, Department of Pathology and Laboratory Medicine, Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin
  • 4Department of Dermatology and Pathology, Harvard Medical School, Boston, Massachusetts
  • 5Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts
Further Information

Publication History

Publication Date:
27 November 2012 (online)

Abstract

Vascular anomalies may be appropriately classified into two broad categories, vascular tumors and vascular malformations, which are distinguished by the presence of cellular proliferation in contrast to aberrations in morphogenesis, respectively. This system of classification is based upon histological features that may in large part be differentiating, but nevertheless, may show morphological overlap. Advances in immunophenotyping allow for more precise diagnoses as well as further delineation of cell origins. In the discussion, we present the clinical, histological, and, when applicable, the immunophenotypic presentation of vascular anomalies commonly seen in infancy and early childhood.