Neuroimaging in the Evaluation of Epilepsy

Naymee J. Velez-Ruiz; Joshua P. Klein

doi:10.1055/s-0032-1331809

Seminars in Neurology, Table of Contents

Semin Neurol 2012; 32(04): 361-373
DOI: 10.1055/s-0032-1331809

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Neuroimaging in the Evaluation of Epilepsy

Authors

Naymee J. Velez-Ruiz

¹Division of Epilepsy, Department of Neurology, Emory University Hospital and Emory University School of Medicine, Atlanta, Georgia
Joshua P. Klein

²Division of Hospital Neurology, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts

Abstract

Neuroimaging has provided extraordinary insight into the pathologic substrate of epilepsy. The excellent spatial resolution and soft tissue contrast of magnetic resonance imaging (MRI) allows identification of a substantial number of pathologies including hippocampal sclerosis, malformations of cortical development, low grade tumors, and vascular abnormalities, among others. Complementary imaging modalities such as positron emission tomography, single photon emission computed tomography, and magnetoencephalography can be diagnostically helpful as well. Identification of a pathologic substrate is particularly important in patients with medically refractory epilepsy who are undergoing evaluation for surgery, and essential in determining the likelihood of seizure freedom after surgical intervention. This article reviews current and emerging neuroimaging techniques in the field of epilepsy.

Keywords

epilepsy - hippocampal sclerosis - cortical malformation - brain tumor - cavernous angioma - neurocutaneous disorder - traumatic brain injury

Full Text

References

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