J Neurol Surg B Skull Base 2013; 74(04): 241-246
DOI: 10.1055/s-0033-1342916
Original Article
Georg Thieme Verlag KG Stuttgart · New York

Concomitant Transsphenoidal Approach to the Anterior Skull Base and Endoscopic Sinus Surgery in Patients with Chronic Rhinosinusitis

Madeleine R. Schaberg
1   Department of Otolaryngology–Head and Neck Surgery, The New York Eye and Ear Infirmary, New York, New York, USA
Gopi B. Shah
2   Department of Otolaryngology–Head and Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
James J. Evans
3   Division of Neuro-Oncologic Neurosurgery and Stereotactic Radiosurgery, Department of Neurological Surgery, Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania, USA
Marc R. Rosen
4   Department of Otolaryngology–Head and Neck Surgery, Thomas Jefferson University, Jefferson Medical College, Philadelphia, Pennsylvania, USA
› Author Affiliations
Further Information

Publication History

20 April 2012

25 January 2012

Publication Date:
03 April 2013 (online)


Objectives To describe outcomes of endoscopic resection of sellar tumors with concomitant endoscopic sinus surgery for patients with chronic rhinosinusitis (CRS).

Design Retrospective chart review.

Setting Tertiary care medical center.

Participants Patients who underwent endoscopic transsphenoidal surgery for excision of anterior skull base lesions and simultaneous functional endoscopic sinus surgery (FESS) for CRS between January 2006 and January 2011 by senior authors (MRR and JJE).

Main Outcomes Measured Short- and long-term postoperative complications.

Results Fourteen patients were identified. Average follow-up was 27 months. All patients had preoperative symptoms consistent with CRS. No patients were treated with preoperative antibiotics. Surgical pathology revealed chronic sinusitis in all specimens. Pathology of the intracranial lesions included 11 pituitary macroadenomas, one craniopharyngioma, one chondrosarcoma, and one cholesterol granuloma. Short-term postoperative morbidities included a sphenoid polyp, one adhesion, and one case of pharyngitis. Long-term outcomes included one frontoethmoidal mucocele, one recurrence of nasal polyps, and three cases of acute sinusitis. There were no intracranial complications for the entire follow-up period.

Conclusions Transsphenoidal surgery can safely be performed in the setting of CRS without increased risk of intracranial complications.

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