Laser- und Lichttherapie von kapillären Malformationen (Nävi flammei)

Zusammenfassung

Kapilläre Malformationen (Nävi flammei) werden bei unter 1 % der Neugeborenen beobachtet. Sie treten überwiegend im Kopf-Hals-Bereich auf und können sehr stigmatisierend für die Betroffenen sein. Blitzlampen-gepumpte gepulste Farbstofflaser stellen weiterhin die Therapie der Wahl dar und können bereits im Säuglingsalter eingesetzt werden. Aber auch inkohärente Lichtquellen wie die Hochenergetische Blitzlampe (HBL) werden zunehmend erfolgreich eingesetzt. Während bei den meisten Patienten eine gute Aufhellung des Nävus flammeus durch die Laser- oder HBL-Therapie erzielt werden kann, wird nur selten ein komplettes Verschwinden der Läsion erreicht. Daher wären neue, effektivere Therapieoptionen wünschenswert.

Abstract

Capillary malformations (port-wine stains) have an incidence below 1 % in neonates. The majority of lesions occur in the head and neck area and may have important cosmetic and psychological implications for the patients. Flashlamp-pumped pulsed dye lasers are still the treatment of choice for the therapy of capillary malformations and can already be used in infancy. Incoherent light sources like Intense pulsed light (IPL) devices are effective for the treatment of capillary malformations, as well. Laser and IPL treatment achieves good clearance in the majority of port-wine stains, but complete clearance is rare. Thus, new therapeutic options are urgently required.

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