Is “QuickView” video preview software of colon capsule endoscopy reliable in the presentation of colorectal polyps?

Background and study aims: Second generation colon capsule endoscopy (CCE) proved a high sensitivity in detection of colorectal polyps (CP). A major limitation is the time consuming video reading. Aim of this prospective, double centre study was to assess the feasibility and accuracy of the previewing mode “QuickView” (QV) of the RAPID reading software, in the presentation of CP in CCE.

Patients and methods: During normal mode reading of 65 CCE videos (mean patient's age 56 years) all frames showing CPs were collected and compared to frames presented by QV at increasing QV-settings (10, 20,...-80%), afterwards. Efficiency of QV in presenting polyps < 6 mm and ≥6 mm (significant polyp), and identifying patients for subsequent therapeutic colonoscopy, capsule egestion rate and cleansing level were assessed.

Results: At a QV-setting of 30%, the QV video presented 89% of the ≥6 mm polyps and 86% of polyps of any size identified in normal mode before with at least one frame (per polyp analysis). A QV-setting of 10% presented at least one frame of ≥6 mm polyps in 98% of the 52 patients demonstrating such polyps in normal mode (per patient analysis). The capsule excretion rate was 74%. Overall colon cleanliness was adequate in 85% of the patients.

Conclusions: A QuickView setting of 30% presents nearly 90% of significant polyps with at least one frame. With respect to the per patient analysis, QV is even more effective at a setting of 10% in determinating patients with significant polyps in more than 95% of the cases.