Kardiologie up2date 2013; 09(04): 271-275
DOI: 10.1055/s-0033-1359202
Hotline – Koronare Herzerkrankung und Atherosklerose
© Georg Thieme Verlag KG Stuttgart · New York

Der vulnerable Patient mit chronischer Niereninsuffizienz

Nikolaus Marx
Jürgen Floege
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Publication History

Publication Date:
14 January 2014 (online)


Patients with chronic kidney disease (CKD) exhibit an increased risk to develop cardiovascular events. Sudden cardiac death is the main reason for the increased cardiovascular mortality in this patient population. Our current understanding suggests that patients with CKD are vulnerable patients and that the increased risk of these patients is determined by the 3 components of the vulnerable blood, the vulnerable vessel and the vulnerable myocardium. The following review discusses the different pathophysiological aspects of the vulnerable patient with CKD and elucidates therapeutic options to reduce the risk for sudden cardiac death in this patient population.