Rofo 2014; 186 - VO402_2
DOI: 10.1055/s-0034-1373463

Immediate comparison of targeted MRI-guided biopsy with systematic transrectal ultrasound guided biopsy in patients with previous negative prostate biopsies

S Kaufmann 1, S Gatidis 1, S Kruck 2, U Kramer 1
  • 1Universität Tübingen, Diagnostische und Interventionelle Radiologie, Tübingen
  • 2Universität Tübingen, Urologie, Tübingen

Zielsetzung:

To directly compare the diagnostic performance of targeted MRI-guided biopsy (MR-GB) and systematic transrectal ultrasound guided biopsy (TRUS-GB).

Material und Methodik:

35 patients with at least one negative TRUS-GB, persistently elevated or rising PSA and a lesion suspicious for prostate cancer (PCa) on 1.5 endorectal coil MRI or 3.0 Tesla MRI were included. In median two targeted biopsies per suspicious lesion on MRI were obtained, systematic TRUS-GB was performed subsequently by an independent urologist without knowledge of the MRI findings. Definite pathology reports were analyzed for anatomical location and criteria of clinical significance.

Ergebnisse:

Tumor detection rate was significantly higher with MR-GB compared with TRUS-GB (16/36, 44% and 8/36, 22% respectively, p < 0.05). MR-GB detected PCa in all patients with postivie TRUS-GB. All tumors detected by MR-GB exhibited at least one criterium of clinical significance.

Schlussfolgerungen:

MR-GB is more effective compared with TRUS-GB in detecting clinically significant PCa in men after previous negative TRUS-GB. PCa detected by MR-GB is located in the peripheral zone as well as in anatomical locations not routinely included in systematic TRUS-GB. Additional systematic biopsy can be omitted in patients undergoing targeted MR-GB.

E-Mail: kaufmann.79@web.de