Facial plast Surg 2014; 30(06): 635-643
DOI: 10.1055/s-0034-1396903
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Oil-Soluble Vitamins: Illegal Use for Lip Augmentation

B. Kamouna1, J. Kazandjieva1, M. Balabanova1, L. Dourmishev1, Z. Negentsova1, D. Etugov1, A. Nikolova1, L. Miteva1, Eckart Haneke2
  • 1Department of Dermatology and Venerology, Faculty of Medicine, University of Sofia, Sofia, Bulgaria
  • 2Department of Dermatology, Inselspital, Universitätsspital Bern, Bern, Switzerland
Further Information

Publication History

Publication Date:
23 December 2014 (online)


Fillers for lip augmentation have become more and more popular in recent years and seem to be indispensable in the cosmetic market nowadays. A series of six young females is presented who developed massive swellings and pain after vitamins A and/or E lip augmentation. The vitamins were extracted from gelatinous capsules (Gericaps [Adipharm EAD, Sofia, Bulgaria], Geritamins [Actavis EAD, Balkanpharma-Dubnitsa AD, Bulgaria], or vitamin E yellow gel capsules) and injected by unprofessional physicians and beauticians in different cosmetic centers. Physical examination revealed firm indurations of the lips and perioral skin, tenderness, erythema, and hard dermal nodules. Histological analysis revealed numerous round-to-ovoid cavities of varying sizes, resulting in a Swiss cheese-like appearance, consistent with lipogranulomas. The patients were treated with systemic and intralesional triamcinolone injections and broad-spectrum antibiotics with good clinical response. In conclusion, these cases demonstrate the danger of the use of unregistered products as fillers injected by unprofessional physicians and beauticians.