Facial plast Surg 2014; 30(06): 647-655
DOI: 10.1055/s-0034-1396905
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Diagnosis and Management of Filler Adverse Effects: An Algorithm

Gabriele Feller-Heppt
1  Skin and Face Clinic, Baden-Baden, Germany
Eckart Haneke
2  Department of Dermatology, Inselspital, Universitätsspital Bern, Bern, Switzerland
Markus V. Heppt
3  Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
23 December 2014 (online)


Fillers are frequently used in beautifying procedures. Despite major advancements of the chemical and biological features of injected materials, filler-related adverse events may occur, and can substantially impact the clinical outcome. Filler granulomas become manifest as visible grains, nodules, or papules around the site of the primary injection. Early recognition and proper treatment of filler-related complications is important because effective treatment options are available. In this report, we provide a comprehensive overview of the differential diagnosis and diagnostics and develop an algorithm of successful therapy regimens.