Facial plast Surg 2014; 30(06): 647-655
DOI: 10.1055/s-0034-1396905
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Diagnosis and Management of Filler Adverse Effects: An Algorithm

Gabriele Feller-Heppt1, Eckart Haneke2, Markus V. Heppt3
  • 1Skin and Face Clinic, Baden-Baden, Germany
  • 2Department of Dermatology, Inselspital, Universitätsspital Bern, Bern, Switzerland
  • 3Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich, Germany
Further Information

Publication History

Publication Date:
23 December 2014 (online)


Fillers are frequently used in beautifying procedures. Despite major advancements of the chemical and biological features of injected materials, filler-related adverse events may occur, and can substantially impact the clinical outcome. Filler granulomas become manifest as visible grains, nodules, or papules around the site of the primary injection. Early recognition and proper treatment of filler-related complications is important because effective treatment options are available. In this report, we provide a comprehensive overview of the differential diagnosis and diagnostics and develop an algorithm of successful therapy regimens.