The Midterm Results of Radiofrequency Ablation and Vagal Denervation in the Surgical Treatment of Long-Standing Atrial Fibrillation Associated with Rheumatic Heart Disease

Zongtao Yin; Huishan Wang; Zengwei Wang; Jinsong Han; Yong Zhang; Hongguang Han

doi:10.1055/s-0034-1396932

The Thoracic and Cardiovascular Surgeon, Table of Contents

Thorac Cardiovasc Surg 2015; 63(03): 250-256
DOI: 10.1055/s-0034-1396932

Original Cardiovascular

Georg Thieme Verlag KG Stuttgart · New York

The Midterm Results of Radiofrequency Ablation and Vagal Denervation in the Surgical Treatment of Long-Standing Atrial Fibrillation Associated with Rheumatic Heart Disease

Authors

Zongtao Yin

¹Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China
Huishan Wang

¹Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China
Zengwei Wang

¹Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China
Jinsong Han

¹Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China
Yong Zhang

¹Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China
Hongguang Han

¹Department of Cardiovascular Surgery, Shenyang Northern Hospital, Shenyang, China

Abstract

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Abstract

Background Though maze III procedure is an effective surgical treatment for atrial fibrillation (AF), the complexity and complications prevent its widespread application. Radiofrequency ablation (RA) has become an accepted therapy, but its chronic effects are still unclear. This retrospective clinical study describes our experience of RA and vagal denervation (VD) in surgical treatment of long-standing AF associated with rheumatic heart disease (RHD) during a 5-year follow-up.

Methods Between June 2006 and December 2007, a total of 173 consecutive patients with long-standing AF-associated RHD underwent mitral valve replacement and ablation maze procedure. In total, 92 cases had RA alone and 81 had RA + VD. Patients were followed up with clinical examination and electrocardiography, and the data were analyzed by multivariable analysis with Cox hazard model.

Results The average follow-up time was 5.0 ± 0.6 years. Multivariable analysis with Cox hazard model revealed that the duration of AF, the size of the left atrium, and tricuspid regurgitation are risk factors for AF recurrence. In addition, long-standing AF ≥ 7 years, left atrium diameter ≥ 58 mm, and severe tricuspid regurgitation may increase the risk of AF recurrence by 2.16-, 2.37-, and 2.67-fold, respectively. Although the freedom from AF during 2 to 5 postoperative years in the RA and RA + VD groups were similar, the percentage of antiarrhythmic drug therapy was higher in the RA group during the early postoperative period (4th month, 54.1 vs. 34.7%, p = 0.017; 5th month, 39.2 vs. 21.3%, p = 0.018; 6th month, 23.0 vs. 10.7%, p = 0.044). Furthermore, the percentage of those free from AF was lower during the 1st year (6th month, 82.2 vs 93.8%, p = 0.023; 1st year, 76.1 vs. 89.9%, p = 0.019).

Conclusion RA is effective for the surgical treatment of long-standing AF associated with rheumatic valve disease. Though vagal denervation helped to maintain a stable sinus rhythm at an early stage, there was no additional benefit after the 1st year of follow-up.

Keywords

atrial fibrillation - radiofrequency - vagal denervation - rheumatic heart disease

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References

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