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Semin Neurol 2015; 35(03): 300-309
DOI: 10.1055/s-0035-1552624
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Mitochondrial Causes of Epilepsy: Evaluation, Diagnosis, and Treatment

Hannah E. Steele
1   Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
2   Department of Neurology, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom
,
Patrick F. Chinnery
1   Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom
2   Department of Neurology, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom
› Author Affiliations
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Publication History

Publication Date:
10 June 2015 (online)

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Abstract

Mitochondrial disorders are frequently associated with seizures. In this review, the authors discuss the seizure patterns and distinguishing features of mitochondrial epilepsy, alongside the indications for investigating, and how to investigate epilepsy from a mitochondrial perspective. Finally, they discuss management strategies for this complex group of patients.

Keywords

epilepsy - mitochondrial disease - investigation - diagnosis - treatment
 

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