Download PDF
TumorDiagnostik & Therapie 2015; 36(07): 416-417
DOI: 10.1055/s-0035-1553895
Thieme Onkologie aktuell
© Georg Thieme Verlag KG Stuttgart · New York

Low back pain as the first presentation of Hürthle cell carcinoma of thyroid

R. V. Botelho
1   Neurosurgeon, Department of Neurosurgery, Hospital do Servidor Público Estadual de São Paulo, IAMSPE, São Paulo, Brazil
,
M. F. de Oliveira
2   Neurosurgery Residency Program – Department of Neurosurgery – Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil
,
S. T. Gameleira Filho
2   Neurosurgery Residency Program – Department of Neurosurgery – Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil
,
J. A. Ferreira
2   Neurosurgery Residency Program – Department of Neurosurgery – Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil
,
L. R. Takahashi
2   Neurosurgery Residency Program – Department of Neurosurgery – Hospital do Servidor Público Estadual de São Paulo, São Paulo, Brazil
,
J. M. Rotta
1   Neurosurgeon, Department of Neurosurgery, Hospital do Servidor Público Estadual de São Paulo, IAMSPE, São Paulo, Brazil
› Author Affiliations
Further Information

Publication History





Publication Date:
29 October 2015 (online)

Also available at
    Permissions and Reprints

Abstract

Hürthle cell carcinoma is a rare variant of differentiated thyroid cancer and occasionally generates distant metastases. There are few reports of Hürthle cell carcinoma metastases to the vertebral column and none with sacral involvement. Here, we report a 48-year-old woman with a 2-year history of moderate low back pain, alleviated with analgesic medication. Her previous medical files were unremarkable. She performed medical evaluation, and a magnetic resonance of lumbar spine revealed a solitary hypointense T2 lesion on the left lamina of S1. The patient was submitted to percutaneous biopsy that displayed carcinomatous pattern compatible with Hürthle cell carcinoma of thyroid. After that, she was submitted to thyroid ultrasound that showed a nodule. Even in the presence of metastases, patients with Hürthle cell carcinoma usually have a relatively good prognosis. We discuss aspects of the diagnosis, management, and surgical treatment of metastatic Hürthle cell carcinoma in reference to the literature.

Keywords

low back pain - spinal diseases - neoplasm metastasis
 

  • References

  • 1 Farooki A, Leung V, Tala H et al. Skeletal-related events due to bone metastases from differentiated thyroid cancer. J Clin Endocrinol Metab 2012; 97: 2433-2439
    CrossrefPubMedGoogle Scholar
  • 2 Pittas AG, Adler M, Fazzari M et al. Bone metastases from thyroid carcinoma: clinical characteristics and prognostic variables in one hundred forty-six patients. Thyroid 2000; 10: 261-268
    CrossrefPubMedGoogle Scholar
  • 3 Sciubba DM, Petteys RJ, Kang S et al. Solitary spinal metastasis of Hürthle cell thyroid carcinoma. J Clin Neurosci 2010; 17: 797-801
    CrossrefPubMedGoogle Scholar
  • 4 Heimann A, Moll U. Spinal metastasis of a thyroglobulin-rich Hürthle cell carcinoma detected by fine needle aspiration. Light and electron microscopic study of an unusual case. Acta Cytol 1989; 33: 639-644
    PubMedGoogle Scholar
  • 5 Demura S, Kawahara N, Murakami H et al. Total en bloc spondylectomy for spinal metastases in thyroid carcinoma. J Neurosurg Spine 2011; 14: 172-176
    CrossrefPubMedGoogle Scholar