Thorac cardiovasc Surg 2018; 66(02): 198-202
DOI: 10.1055/s-0035-1558994
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Local Anesthetics delivered through Pleural Drainages improve Pain and Lung Function after Cardiac Surgery

Bakr Mashaqi
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
Both the authors contributed equally to this work.
,
Issam Ismail
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
Both the authors contributed equally to this work.
,
Thierry T. Siemeni
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
,
Stefan Ruemke
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
,
Felix Fleissner
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
,
Ruoyu Zhang
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
,
Bettina Wiegmann
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
,
Joerg Filitz
Department of Anesthesiology and Intensive Care, Hannover Medical School, Hanover, Germany
,
Jens Gottlieb
Department of Respiratory Medicine, Hannover Medical School, Hanover, Germany
,
Axel Haverich
Department of Thoracic, Transplant and Cardiovascular Surgery, Hannover Medical School, Hannover, Germany
› Author Affiliations
Further Information

Publication History

23 April 2015

09 June 2015

Publication Date:
03 September 2015 (eFirst)

Abstract

Objective Pleural tubes after coronary artery bypass graft (CABG) surgery usually cause pain resulting interalia in an impact of postoperative breathing. Therefore, the influence of intrapleural lidocaine application through special double-lumen chest tubes with respect to pain relief and lung function was investigated and compared with placebo.

Methods In this study, 40 patients who underwent CABG got intrapleural injection either with 2% lidocaine (n = 20) or placebo (0.9% saline solution) (n = 20) on the first 2 days after surgery. Pain was measured by pain intensity numeric rating scale (NRS) (0 = no pain; 10 = the most intense pain) and lung function by portable spirometer.

Results On the first postoperative day (POD1), mean pain reduction was NRS 1.9 for the lidocaine group with an improvement of the forced expiratory volume in 1 second (FEV1) of 0.51 L. Similar results were shown on the second postoperative day (POD2) with a decreased pain level of mean NRS 1.65 and an FEV1 improvement of 0.26 L. In comparison, results of the placebo group showed no significant pain reduction, neither on the POD1 (NRS 0.35; p = 0.429) nor on the POD2 (NRS 0.55; p = 0.159). Also, there was no significant influence of FEV1 after placebo on the POD1 (FEV1 = 0.048 L; p = 0.70) or on the POD2 (FEV1 = 0.0135 L; p = 0.925).

Conclusion Intrapleural application of lidocaine is a safe and feasible method to reduce drainage-related pain and improving lung function after CABG.