Synthesis, Table of Contents Synthesis 2017; 49(17): 3945-3951DOI: 10.1055/s-0036-1588813 special topic © Georg Thieme Verlag Stuttgart · New YorkEthylene Glycol Assisted Intermolecular Pauson–Khand Reaction Authors Author Affiliations Albert Cabré a Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, Barcelona 08028, Spain Email: antoni.riera@irbbarcelona.org Email: xavier.verdaguer@irbbarcelona.org Xavier Verdaguer * a Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, Barcelona 08028, Spain Email: antoni.riera@irbbarcelona.org Email: xavier.verdaguer@irbbarcelona.org b Departament de Química Inorgànica i Orgànica, Secció Orgànica, Universitat de Barcelona, Martí i Franquès 1, Barcelona 08028, Spain Antoni Riera * a Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Baldiri Reixac 10, Barcelona 08028, Spain Email: antoni.riera@irbbarcelona.org Email: xavier.verdaguer@irbbarcelona.org b Departament de Química Inorgànica i Orgànica, Secció Orgànica, Universitat de Barcelona, Martí i Franquès 1, Barcelona 08028, Spain Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Published as part of the Special Topic Cobalt in Organic Synthesis Abstract The use of ethylene glycol as additive in the N-oxide-promoted intermolecular Pauson–Khand reaction (PKR) has been studied. The addition of 15% ethylene glycol to the reaction mixture consistently increased (from 20% up to 2–4-fold) the reaction yields. Key words Key wordsPauson–Khand reaction - cobalt - ethylene glycol - cyclopentenones - cycloaddition Full Text References References 1a Omae I. Appl. Organomet. Chem. 2007; 21: 318 1b Strübing D. Beller M. In Catalytic Carbonylation Reactions . Beller M. Springer; Berlin: 2006: 165 1c Pérez-Castells J. In Metal Catalyzed Cascade Reactions . Müller TJ. J. Springer; Berlin: 2006: 207 1d Laschat S. Becheanu A. Bell T. Baro A. Synlett 2005; 2547 1e Boñaga LV. R. Krafft ME. Tetrahedron 2004; 60: 9795 1f Rodríguez Rivero M. Adrio J. Carretero JC. Eur. J. Org. Chem. 2002; 2881 1g Brummond KM. Kent JL. Tetrahedron 2000; 56: 3263 1h Fletcher AJ. Christie SD. R. J. Chem. Soc., Perkin Trans. 1 2000; 1657 2a Chuang KV. Xu C. Reisman SE. Science 2016; 353: 912 2b Verdaguer X. Science 2016; 353: 866 2c Gibson SE. Mainolfi N. Angew. Chem. Int. 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