Thorac cardiovasc Surg
DOI: 10.1055/s-0036-1592192
Original Thoracic
Georg Thieme Verlag KG Stuttgart · New York

Bronchial Stump Recurrence after Complete Resection of Lung Cancer: Effect of the Distance between the Tumor and Bronchial Resection Margin

Mehmet Zeki Gunluoglu1, Celalettin Ibrahim Kocaturk1, Adalet Demir1, Halide Nur Urer2, Seyyit Ibrahim Dincer1, Mehmet Ali Bedirhan1
  • 1Department of Thoracic Surgery, Yedikule Chest Diseases and Thoracic Surgery Education and Research Hospital, Istanbul, Turkey
  • 2Department of Pathology, Yedikule Chest Diseases and Thoracic Surgery Education and Research Hospital, Istanbul, Turkey
Further Information

Publication History

14 April 2016

03 August 2016

Publication Date:
13 September 2016 (eFirst)

Abstract

Purpose The purpose of this study was to evaluate the following parameters after complete resection in established lung cancer patients: the frequency of bronchial stump recurrence (BSR), the effect of the distance between the tumor and bronchial resection margin (DBTM) on BSR, the survival of patients with BSR, and the effect of the DBTM on survival.

Patients and Methods We retrospectively evaluated 553 consecutive lung cancer patients who underwent complete lung resection. The patients were classified as DBTM: ≤ 10 mm (group 1), 11 to 20 mm (group 2), and > 20 mm (group 3).

Results We found BSR in eight (1.5%) patients. Six patients were in group 1, and two were in group 2. The difference was found to be statistically significant (p = 0004; groups 1 vs. 3). In multivariable analysis, we observed a trend toward significance for the effect of a DBTM on BSR development (p = 0.1). The DBTM did not significantly affect survival (p = 0.61). The survival of patients who developed BSR was significantly poor compared with those who did not develop BSR (p = 0.001).

Conclusion BSR can develop even after complete resection of lung cancer. The DBTM is associated with BSR risk, and the survival of patients who develop BSR is poor.