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Semin Musculoskelet Radiol 2016; 20(05): 441-452
DOI: 10.1055/s-0036-1594284
DOI: 10.1055/s-0036-1594284
Review Article
Botulinum Toxin Injections in Musculoskeletal Disorders
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
21. Dezember 2016 (online)
Abstract
Botulinum toxin (BTX) is used for multiple clinical indications due to its ability to induce temporary chemodenervation and muscle paralysis. This property has supported its application in treating a variety of musculoskeletal conditions, especially those involving muscular hyperactivity and contractures such as cerebral palsy and dystonia. However, off-label use of BTX injection in other musculoskeletal disorders is gaining increased acceptance, such as in neurogenic thoracic outlet syndrome, epicondylitis, and shoulder pain after stroke. This review discusses the mechanism of action, best practices, and current indications of BTX injections in the musculoskeletal system. We also discuss the state of the science regarding BTX injections for musculoskeletal disorders and the available evidence supporting its use.
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