Facial Plast Surg 2016; 32(06): 656-661
DOI: 10.1055/s-0036-1596045
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Isotretinoin Use in Thick-Skinned Rhinoplasty Patients

Roxana Cobo
1  Division of Facial Plastic Surgery, Department of Otolaryngology, Centro Medico Imbanaco, Cali, Colombia
Liliana Vitery
2  Department of Otolaryngology, Rivas Clinic, Bogota, Colombia
› Author Affiliations
Further Information

Publication History

Publication Date:
29 December 2016 (online)


One of the characteristics of mestizo patients can be the thick sebaceous skin associated with a poor osteocartilaginous underlying nasal structure. In spite of using a proper structural approach where grafts and sutures are used to define the nasal tip, frequently the results are suboptimal. Surgical techniques have been described to reduce the thickness of the skin-soft tissue envelope, but these frequently give unreliable results. The monitored use of isotretinoin given orally as a complement after performing a rhinoplasty can adequately control the production of the sebaceous glands and thin the skin-subcutaneous tissue envelope in a uniform fashion without compromising the underlying bony and cartilaginous structures of the nose. Patients ideally should be treated jointly with a dermatologist and be followed closely to monitor hepatic function. Follow-up after 2 years with pre- and postoperative pictures shows improved definition of the nasal tip and dramatic improvement on sebaceous gland production.