Is there an association between physical activity and lung function in lung-healthy German adults? – Results from the KORA FF4 study
23 February 2017 (online)
Being active is associated with beneficial health effects for subjects with chronic lung diseases. The association of physical activity (PA) with lung function in lung-healthy populations has been rarely analysed. Therefore, our aim was to investigate the association of accelerometer-based PA with spirometric parameters, maximal inspiratory mouth pressure (PImax) and pulmonary gas exchange capacity related to alveolar volume (TLCO/VA) in lung-healthy adults from the KORA FF4 cohort.
Data was available from 341 participants (45% males, mean age 57 years, 47% never-smokers) without chronic lung diseases and FEV1/FVC ≥0.7 who completed lung function testing and wore ActiGraph GT3X accelerometers on the hip for up to seven days. According to their mean minutes/day spent in moderate to vigorous PA (MVPA), subjects were classified into activity quartiles. Other analysed PA variables were the achievement of at least one 10-minute bout of MVPA, and meeting the WHO activity recommendation threshold of 150 minutes/week of MVPA spent in bouts of at least 10 minutes. Linear regression models adjusted for possible confounders were applied.
Associations of MVPA quartiles with FEV1, FVC and GLI z-scores of FEV1 and FVC were found. In regression analyses, FVC was 157 ml higher in subjects engaging on average > 48 minutes/day in MVPA (4th quartile) compared to those with < 20 minutes/day (1st quartile). FEV1 was 139 ml higher comparing these quartiles. No associations were found for TLCO/VA. Engaging in MVPA for at least one 10-minute bout length was associated with higher PImax. Achieving the WHO PA recommendations was not associated with any lung function parameter.
Weak, but positive associations of PA with lung function suggest that engaging in PA might benefit lung function of adults without chronic lung diseases.