Semin Respir Crit Care Med 2017; 38(02): 174-184
DOI: 10.1055/s-0037-1602375
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Pulmonary Infections in Pregnancy

Jyoti S. Mathad
1  Department of Medicine, Weill Cornell Medicine, Center for Global Health, New York, New York
Amita Gupta
2  Department of Medicine and International Health, Johns Hopkins University, Center for Clinical Global Health Education, Baltimore, Maryland
› Author Affiliations
Further Information

Publication History

Publication Date:
22 May 2017 (online)


Pregnant women experience physiological and immunological changes that increase the risk or severity of certain pulmonary infections. These changes also affect drug disposition, which impacts treatment choices. In this article, we review the available data on (1) the physiological and immunological changes that specifically impact tuberculosis, influenza, and varicella pneumonia; (2) active and latent tuberculosis management, including drug monitoring and maternal–infant outcomes; (3) the treatment and prevention of influenza; and (4) the diagnosis and management of varicella pneumonia. Clinical trials often exclude pregnant women, but there is a consensus that treating pregnant women for tuberculosis, influenza, and varicella pneumonia improves outcomes for both the woman and her child.