Thorac cardiovasc Surg
DOI: 10.1055/s-0037-1603790
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Postoperative Complications and Long-Term Results after Primary Cardiac Sarcoma Resection

Erhan Kavakbasi
Department of Psychiatry and Psychotherapy, University of Münster, Münster, Germany
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Münster, Münster, Germany
,
Hans Heinrich Scheld
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Münster, Münster, Germany
,
Torsten Kessler
Department of Medicine A, University of Münster, Münster, Germany
,
Jürgen R. Sindermann
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Münster, Münster, Germany
,
Volkan Kösek
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Münster, Münster, Germany
,
T. D. T. Tjan
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Münster, Münster, Germany
,
Sven Martens
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Münster, Münster, Germany
,
Andreas Hoffmeier
Division of Cardiac Surgery, Department of Cardiothoracic Surgery, University of Münster, Münster, Germany
› Author Affiliations
Further Information

Publication History

14 February 2017

30 April 2017

Publication Date:
11 June 2017 (eFirst)

Abstract

Background Primary malignant cardiac tumors rarely occur in clinical care. Little is known about the impact of a parameter on postoperative survival.

Methods From May 1991 to May 2014, a total of 24 patients underwent surgical treatment of a primary cardiac sarcoma in our center. We analyzed our clinical database retrospectively for information on patient characteristics and treatment data. The follow-up could be completed to 91.7%.

Results Angiosarcoma and non-otherwise-specified sarcoma were the most common tumor entities. R0 resection was achieved in most cases. Postoperative mortality within the first 30 days was 20.8% (n = 5). In four of these five cases, postoperative low-output cardiac failure was the leading cause of death. The cumulative survival rate was 77.3% after 30 days, 68.2% after 3 months, 50.0% after 6 months, 45.0% after 12 months, and 18.0% after 24 months. The mean survival time in the whole group was 47.0 months. A low tumor differentiation was associated with low mean survival, but this was not statistically significant. Mean survival of sarcoma was higher after R0 resection. There was no significant rate of survival difference regarding the adjuvant therapy concept.

Conclusion Extended surgery alone or in combination with chemo- and/or radiotherapy may be successful in certain cases and may offer a satisfactory quality of life. The establishment of a multicenter heart tumor register in Germany is necessary to increase the number of cases in studies, get more remarkable study results, and standardize the diagnosis and therapy.