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Thromb Haemost 1998; 80(02): 345-346
DOI: 10.1055/s-0037-1615202
Letters to the Editor
Schattauer GmbH

C-399T Polymorphism in the Promoter Region of Human Tissue Factor Pathway Inhibitor (TFPI) Gene Does not Change the Plasma TFPI Antigen Level and Does not Cause Venous Thrombosis

Toshiyuki Miyata
1   Research Institute
,
Toshiyuki Sakata
2   Department of Clinical Laboratory
,
Kousuke Kumeda
3   Chemo-Sero-Therapeutic Research Institute, Kumamoto
,
Kagehiro Uchida
4   FALCO Bio Systems Ltd, Kuze-gun, Kyoto
,
Motoo Tsushima
5   Department of Internal Medicine, National Cardiovascular Center, Suita, Osaka
,
Hironobu Fujimura
6   Department of Surgery II, Osaka University Medical School, Suita, Japan
,
Tomio Kawasaki
6   Department of Surgery II, Osaka University Medical School, Suita, Japan
,
Hisao Kato
1   Research Institute
› Author Affiliations
Further Information

Publication History

Received 14 August 1997

Accepted after resubmission 07 April 1998

Publication Date:
08 December 2017 (online)

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  • References

  • 1 Broze Jr GJ. The role of tissue factor pathway inhibitor in a revised coagulation cascade. Semin Hematol 1992; 29: 159-69.
    PubMedGoogle Scholar
  • 2 Wun TC. Tissue factor pathway inhibitor. In: Molecular Basis of Thrombosis and Hemostasis. High KA, Roberts HR. (eds). Marcel Dekker; New York: 1995. pp 331-53.
    Google Scholar
  • 3 van der Logt CPE, Reitsma PH, Bertina RM. Intron-exon organization of the human gene coding for the lipoprotein-associated coagulation inhibitor: The factor Xa dependent inhibitor of the extrinsic pathway of coagulation. Biochemistry 1991; 30: 1571-7.
    CrossrefPubMedGoogle Scholar
  • 4 Girard TJ, Eddy R, Wesselschmidt RL, MacPhail LA, Likert KM, Byers MG, Shows TB, Broze Jr GJ. Structure of the human lipoprotein-associated coagulation inhibitor gene. Intron/exon gene organization and localization of the gene to chromosome 2. J Biol Chem 1991; 266: 5036-41.
    PubMedGoogle Scholar
  • 5 Enjyoji K, Emi M, Mukai T, Imada M, Leppert ML, Lalouel JM, Kato H. Human tissue factor pathway inhibitor (TFPI) gene: Complete genomic structure and localization on the genetic map of chromosome 2q. Genomics 1993; 17: 423-8.
    CrossrefPubMedGoogle Scholar
  • 6 Maruyama C, Tsushima M, Kyotani S, Nakamori T, Fukushima S, Maruyama T. Cerebral blood flow velocity and serum fatty acid composition. Nutr Metab Cardiovasc Dis 1996; 6: 81-9.
    PubMedGoogle Scholar
  • 7 Miyata T, Sakata T, Zheng YZ, Tsukamoto H, Umeyama H, Uchiyama S, Ikusaka M, Yoshioka A, Imanaka Y, Fujimura H, Kambayashi J, Kato H. Genetic characterization of protein C deficiency in Japanese subjects using a rapid and nonradioactive method for single-stand conformational polymorphism analysis and a model building. Thromb Haemost 1996; 76: 302-11.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 8 Kamikura Y, Wada H, Yamada A, Shimura M, Hiyoyama K, Shiku H, Tanigawa M, Nishikawa H, Yamada N, Isaka N, Nakano T, Kumeda K, Kato H. Increased tissue factor pathway inhibitor in patients with acute myocardial infarction. Am J Hematol 1997; 55: 183-7.
    CrossrefPubMedGoogle Scholar