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Hamostaseologie 2007; 27(01): 5-12
DOI: 10.1055/s-0037-1616894
DOI: 10.1055/s-0037-1616894
Orginal Articles
Oxidative stress and endothelial dysfunction
Oxidative stress und endotheliale DysfunckionFurther Information
Publication History
Publication Date:
27 December 2017 (online)
Summary
This review focuses on the role of vascular oxidative stress in the development and progression of endothelial dysfunction. We discuss different sources of oxidative stress in the vessel wall, oxidative stress and coagulation, the role of oxidative stress and vascular function in arteries and veins, the flow-dependent regulation of reactive oxygen species, the putative impact of oxidative stress on atherosclerosis, the interaction of angiotensin II, oxidative stress and endothelial dysfunction, and clinical implications.
Zusammenfassung
Diese Übersichtsarbeit fokussiert auf die Rolle von vaskulärem oxidativen Stress in der Entwicklung und Progression von endothelialer Dysfunktion. Wir diskutieren unterschiedliche Quellen reaktiver Sauerstoffspezies in der Gefäßwand, oxidativen Stress und Koagulation, die Rolle von oxidativem Stress und Gefäßfunktion in Arterien und Venen, die flussabhängige Regulation von reaktiven Sauerstoffspezies, den möglichen Einfluss von oxidativem Stress auf die Atherosklerose, die Interaktion von Angiotensin II, oxidativem Stress und endothelialer Dysfunktion und klinische Implikationen.
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